Showing pharmacokinetics for Protocatechuic acid metabolite after consumption of Cocoa, powder in humans Metabolism
Urpi-Sarda M., Llorach R., Khan N., Monagas M., Rotches-Ribalta M., Lamuela-Raventos R., Estruch R., Tinahones F.J., Andres-Lacueva C. (2010) Effect of milk on the urinary excretion of microbial phenolic acids after cocoa powder consumption in humans. J Agric Food Chem 58:4706-11 PubMed (20222713)
Urine analysed after enzymatic deconjugation
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| Excretion in Urine (nmol/mg creatinine) | |||||||
|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (hours) |
Polyphenol Source Name as described in publication |
|||
| 0 | 6 | 12 | 24 | ||||
| 1 | 40 g | Single Dose | 2.9 | 8.88 | 3.36 | 5.18 |
cocoa powder in whole milk
|
| 2 | 40 g | Single Dose | 4.33 | 11.07 | 5.58 | 5.05 |
cocoa powder in water
|