Showing pharmacokinetics for Daidzein metabolite after consumption of Daidzein in humans Metabolism

Rufer C.E., Bub A., Moseneder J., Winterhalter P., Sturtz M., Kulling S.E. (2008) Pharmacokinetics of the soybean isoflavone daidzein in its aglycone and glucoside form: a randomized, double-blind, crossover study. Am J Clin Nutr 87:1314-23 PubMed (18469255)

Plasma and Urine analysed after enzymatic deconjugation

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Plasma Concentration (µmol/L)
Number Dose Multiple Dose Duration Time (hours) Polyphenol Source
Name as described in publication
0 1 3 6 12 24
1 1 capsule Single Dose 0 0 0.2 0.4 0.35 0
daidzein capsule
L)&chxp=1,50|3,50&chd=t:0.0,1.0,3.0,6.0,12.0,24.0|0.0,0.0,0.2,0.4,0.35,0
Cumulative Excretion in Urine (µmol)
Number Dose Multiple Dose Duration Time (hours) Polyphenol Source
Name as described in publication
0 6 12 24
1 1 capsule Single Dose 0 4 19 31
daidzein capsule
Chart?cht=lxy&chs=600x300&chf=bg,s,fafafa&chxt=x,x,y&chxr=0,0.0,24.240000000000002,2|2,0.0,31.31,2&chds=0.0,24.240000000000002,0.0,31.31&chxl=1:|time+after+ingestion+(hours)&chtt=cumulative+excretion+in+urine+(µmol)&chxp=1,50|3,50&chd=t:0.0,6.0,12.0,24.0|0.0,4.0,19.0,31