Showing pharmacokinetics for Daidzein metabolite after consumption of Daidzein 7-O-glucoside in humans Metabolism

Rufer C.E., Bub A., Moseneder J., Winterhalter P., Sturtz M., Kulling S.E. (2008) Pharmacokinetics of the soybean isoflavone daidzein in its aglycone and glucoside form: a randomized, double-blind, crossover study. Am J Clin Nutr 87:1314-23 PubMed (18469255)

Plasma and Urine analysed after enzymatic deconjugation

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Plasma Concentration (µmol/L)
Number Dose Multiple Dose Duration Time (hours) Polyphenol Source
Name as described in publication
0 1 3 6 12 24
1 1 capsule Single Dose 0 0 1.1 1.8 2.5 1.8
daidzein-7-O-glucoside capsule
L)&chxp=1,50|3,50&chd=t:0.0,1.0,3.0,6.0,12.0,24.0|0.0,0.0,1.1,1.8,2.5,1
Cumulative Excretion in Urine (µmol)
Number Dose Multiple Dose Duration Time (hours) Polyphenol Source
Name as described in publication
0 6 12 24
1 1 capsule Single Dose 0 20 70 107
daidzein-7-O-glucoside capsule
Chart?cht=lxy&chs=600x300&chf=bg,s,fafafa&chxt=x,x,y&chxr=0,0.0,24.240000000000002,2|2,0.0,108.07000000000001,10&chds=0.0,24.240000000000002,0.0,108.07000000000001&chxl=1:|time+after+ingestion+(hours)&chtt=cumulative+excretion+in+urine+(µmol)&chxp=1,50|3,50&chd=t:0.0,6.0,12.0,24.0|0.0,20.0,70.0,107