Showing pharmacokinetics for 5-(3',4',-dihydroxyphenyl)-γ-valerolactone metabolite after consumption of various sources Metabolism
Meng X., Sang S., Zhu N., Lu H., Sheng S., Lee M.J., Ho C.T., Yang C.S. (2002) Identification and characterization of methylated and ring-fission metabolites of tea catechins formed in humans, mice, and rats. Chem Res Toxicol 15:1042-50 PubMed (12184788)
Urine analysed after enzymatic deconjugation
| Excretion in Urine (µmol/L) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (hours) |
Polyphenol Source Name as described in publication |
|||||
| 0 | 3 | 6 | 9 | 18 | 24 | ||||
| 1 | 200 mg | Single Dose | 0 | 2 | 4.7 | 1.8 | 0.5 | 0 |
epigallocatechin gallate
|
| 2 | 200 mg | Single Dose | 0 | 0 | 4 | 3 | 0 | 0 |
epigallocatechin
|
| 3 | 200 mg | Single Dose | 0 | 1.7 | 4.7 | 3.5 | 1.8 | 0 |
epicatechin
|