Showing pharmacokinetics for metabolites after consumption of Tea [green], powder in humans Metabolism

Li C., Lee M.J., Sheng S., Meng X., Prabhu S., Winnik B., Huang B., Chung J.Y., Yan S., Ho C.T., Yang C.S. (2000) Structural identification of two metabolites of catechins and their kinetics in human urine and blood after tea ingestion. Chem Res Toxicol 13:177-84 PubMed (10725114)

Urine analysed after enzymatic deconjugation

Cumulative Excretion in Urine (mg)
Number Dose Multiple Dose Duration Time (hours) Metabolite
0 0.5 2 4.5 7.5 10.5
1 1.2 g Single Dose 0 150 490 585 597 597
(-)-Epigallocatechin
2 1.2 g Single Dose 0 100 275 315 325 325
(-)-Epicatechin
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