Showing pharmacokinetics for metabolites after consumption of Soy, powder, baked in humans Metabolism
Watanabe S., Yamaguchi M., Sobue T., Takahashi T., Miura T., Arai Y., Mazur W., Wahala K., Adlercreutz H. (1998) Pharmacokinetics of soybean isoflavones in plasma, urine and feces of men after ingestion of 60 g baked soybean powder (kinako). J Nutr 128:1710-5
Plasma analysed after enzymatic deconjugation
Plasma Concentration (µmol/L) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Number | Dose | Multiple Dose Duration | Time (hours) | Metabolite | ||||||
0 | 6 | 8 | 12 | 24 | 72 | |||||
1 | 60 g | Single Dose | 0 | 1.5 | 1.2 | 0.8 | 0.2 | 0 |
Daidzein
|
|
2 | 60 g | Single Dose | 0 | 2.4 | 2.1 | 1.8 | 0.8 | 0.1 |
Genistein
|
|
3 | 60 g | Single Dose | 0 | 0.03 | 0.3 | 0.35 | 0.1 | 0 |
Equol
|
|
4 | 60 g | Single Dose | 0 | 0.11 | 0.25 | 0.2 | 0.16 | 0 |
O-Desmethylangolensin
|