Showing pharmacokinetics for metabolites after consumption of Quercetin in humans Metabolism

Soleas G.J., Yan J., Goldberg D.M. (2001) Measurement of trans-resveratrol, (+)-catechin, and quercetin in rat and human blood and urine by gas chromatography with mass selective detection. Methods Enzymol 335:130-45 PubMed (11400362)

Plasma and Urine analysed after enzymatic deconjugation

Plasma Concentration (µg/L)
Number Dose Multiple Dose Duration Time (hours) Metabolite
0 0.5 1 2 4
1 25 mg Single Dose 3.03 17.04 15.32 9.49 6.35
(+)-Catechin
L)&chxp=1,50|3,50&chd=t:0.0,0.5,1.0,2.0,4.0|3.03,17.04,15.32,9.49,6
Excretion in Urine (µg/L)
Number Dose Multiple Dose Duration Time (hours) Metabolite
0 1 2 3 4 6
1 25 mg Single Dose 74.3 2425.4 3233.6 139 216.4 33.8
(+)-Catechin
L)&chxp=1,50|3,50&chd=t:0.0,1.0,2.0,3.0,4.0,6.0|74.3,2425.4,3233.6,139.0,216.4,33