Showing pharmacokinetics for Genistein metabolite after consumption of Soy, milk in humans Metabolism

Kano M., Takayanagi T., Harada K., Sawada S., Ishikawa F. (2006) Bioavailability of isoflavones after ingestion of soy beverages in healthy adults. J Nutr 136:2291-6 PubMed (16920843)

Plasma and Urine analysed after enzymatic deconjugation

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Plasma Concentration (µmol/L)
Number Dose Multiple Dose Duration Time (hours) Polyphenol Source
Name as described in publication
0 1 3 5 8 24
1 100 mL Single Dose 0 0.15 0.13 0.3 0.3 0
soy milk
L)&chxp=1,50|3,50&chd=t:0.0,1.0,3.0,5.0,8.0,24.0|0.0,0.15,0.13,0.3,0.3,0
Cumulative Excretion in Urine (µmol)
Number Dose Multiple Dose Duration Time (hours) Polyphenol Source
Name as described in publication
0 2 6 12 24 48
1 100 mL Single Dose 0 0.5 3 6 7.8 8.7
soy milk
Chart?cht=lxy&chs=600x300&chf=bg,s,fafafa&chxt=x,x,y&chxr=0,0.0,48.480000000000004,2|2,0.0,8.786999999999999,1&chds=0.0,48.480000000000004,0.0,8.786999999999999&chxl=1:|time+after+ingestion+(hours)&chtt=cumulative+excretion+in+urine+(µmol)&chxp=1,50|3,50&chd=t:0.0,2.0,6.0,12.0,24.0,48.0|0.0,0.5,3.0,6.0,7.8,8