Showing pharmacokinetics for Genistein metabolite after consumption of various sources Metabolism
Kano M., Takayanagi T., Harada K., Sawada S., Ishikawa F. (2006) Bioavailability of isoflavones after ingestion of soy beverages in healthy adults. J Nutr 136:2291-6 PubMed (16920843)
Plasma and Urine analysed after enzymatic deconjugation
| Plasma Concentration (µmol/L) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (hours) |
Polyphenol Source Name as described in publication |
|||||
| 0 | 1 | 3 | 5 | 8 | 24 | ||||
| 1 | 100 mL | Single Dose | 0 | 0.15 | 0.13 | 0.3 | 0.3 | 0 |
soy milk
|
| 2 | 100 mL | Single Dose | 0 | 0.89 | 0.45 | 0.6 | 0.45 | 0.5 |
fermented soy milk
|
| 3 | 100 mL | Single Dose | 0 | 1.1 | 0.58 | 0.6 | 0.55 | 0.13 |
enzyme-treated soy milk
|
| Cumulative Excretion in Urine (µmol) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (hours) |
Polyphenol Source Name as described in publication |
|||||
| 0 | 2 | 6 | 12 | 24 | 48 | ||||
| 1 | 100 mL | Single Dose | 0 | 0.5 | 3 | 6 | 7.8 | 8.7 |
soy milk
|
| 2 | 100 mL | Single Dose | 0 | 3.1 | 7.5 | 11 | 13.5 | 14.1 |
fermented soy milk
|
| 3 | 100 mL | Single Dose | 0 | 2.9 | 6.5 | 10 | 12.5 | 13.1 |
enzyme-treated soy milk
|