Showing pharmacokinetics for metabolites after consumption of trans-Resveratrol in humans Metabolism
Soleas G.J., Yan J., Goldberg D.M. (2001) Measurement of trans-resveratrol, (+)-catechin, and quercetin in rat and human blood and urine by gas chromatography with mass selective detection. Methods Enzymol 335:130-45 PubMed (11400362)
Plasma and Urine analysed after enzymatic deconjugation
| Plasma Concentration (µg/L) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (hours) | Metabolite | |||||
| 0 | 0.5 | 1 | 2 | 4 | |||||
| 1 | 25 mg | Single Dose | 4.7 | 345.1 | 220.9 | 98.4 | 54.1 |
Trans-Resveratrol
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| Excretion in Urine (µg/L) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (hours) | Metabolite | ||||||
| 0 | 1 | 2 | 3 | 4 | 6 | |||||
| 1 | 25 mg | Single Dose | 115 | 7155 | 7963 | 3750 | 2904 | 830.8 |
Trans-Resveratrol
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