Showing pharmacokinetics for (-)-Epicatechin metabolite after consumption of various sources Metabolism

Baba S., Osakabe N., Natsume M., Muto Y., Takizawa T., Terao J. (2001) In vivo comparison of the bioavailability of (+)-catechin, (-)-epicatechin and their mixture in orally administered rats. J Nutr 131:2885-91 PubMed (11694613)

Plasma analysed after enzymatic deconjugation

Plasma Concentration (µmol/L)
Number Dose Multiple Dose Duration Time (minutes) Polyphenol Source
Name as described in publication
0 30 60 120 180 300
1 172 µmol/kg bw Single Dose 0 35 34 18 15 8
epicatechin
2 172 µmol/kg bw Single Dose 0 17 21 19 16 10
mixture of catechin and epicatechin
L)&chxp=1,50|3,50&chd=t:0.0,30.0,60.0,120.0,180.0,300.0|0.0,35.0,34.0,18.0,15.0,8.0|0.0,30.0,60.0,120.0,180.0,300.0|0.0,17.0,21.0,19.0,16.0,10