Showing pharmacokinetics for 3'-O-Methylcatechin metabolite after consumption of Wine, powder in rats Metabolism
Gonthier M.P., Cheynier V., Donovan J.L., Manach C., Morand C., Mila I., Lapierre C., Remesy C., Scalbert A. (2003) Microbial aromatic acid metabolites formed in the gut account for a major fraction of the polyphenols excreted in urine of rats fed red wine polyphenols. J Nutr 133:461-7
Plasma and Urine analysed after enzymatic deconjugation
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| Cumulative Excretion in Urine (mg) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (days) |
Polyphenol Source Name as described in publication |
|||||
| 0 | 1 | 2 | 4 | 6 | 8 | ||||
| 1 | 0.25 g/100 g bw | Single Dose | 0.7 | 1.9 | 3.2 | 6 | 9.6 | 13.2 |
wine powder
|
| 2 | 0.5 g/100 g bw | Single Dose | 0 | 0.5 | 0.9 | 1.7 | 2.5 | 3.3 |
wine powder
|
| 3 | 0.5 g/100 g bw | Single Dose | 0.7 | 1.9 | 3.9 | 9.1 | 15.1 | 20.9 |
wine powder
|