Showing pharmacokinetics for Cyanidin 3-O-rutinoside metabolite after consumption of Blackcurrant, juice in humans Metabolism

Rechner A.R., Kuhnle G., Hu H., Roedig-Penman A., van den Braak M.H., Moore K.P., Rice-Evans C.A. (2002) The metabolism of dietary polyphenols and the relevance to circulating levels of conjugated metabolites. Free Radic Res 36:1229-41

Plasma and Urine analysed without enzymatic deconjugation

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Plasma Concentration (nmol/L)
Number Dose Multiple Dose Duration Time (hours) Polyphenol Source
Name as described in publication
0 1 2 4 6
1 330 mL Single Dose 0 24.4 12.9 3.6 0
blackcurrant juice
L)&chxp=1,50|3,50&chd=t:0.0,1.0,2.0,4.0,6.0|0.0,24.4,12.9,3.6,0
Cumulative Excretion in Urine (mg)
Number Dose Multiple Dose Duration Time (minutes) Polyphenol Source
Name as described in publication
0 10 45 100 160 240
1 330 mL Single Dose 0 0 0.21 0.28 0.31 0.31
blackcurrant juice
Chart?cht=lxy&chs=600x300&chf=bg,s,fafafa&chxt=x,x,y&chxr=0,0.0,242.4,20|2,0.0,0.3131,0.03131&chds=0.0,242.4,0.0,0.3131&chxl=1:|time+after+ingestion+(minutes)&chtt=cumulative+excretion+in+urine+(mg)&chxp=1,50|3,50&chd=t:0.0,10.0,45.0,100.0,160.0,240.0|0.0,0.0,0.21,0.28,0.31,0