Showing pharmacokinetics for metabolites after consumption of Orange [Blood], pure juice in humans Metabolism
Vitaglione P., Donnarumma G., Napolitano A., Galvano F., Gallo A., Scalfi L., Fogliano V. (2007) Protocatechuic acid is the major human metabolite of cyanidin-glucosides. J Nutr 137:2043-8 PubMed (17709440)
Plasma and Urine analysed without enzymatic deconjugation
| Excretion in Urine (nmol/mmol creatinine) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (hours) | Metabolite | ||||||
| 0 | 2 | 4 | 6 | 12 | 24 | |||||
| 1 | 1 L | Single Dose | 0 | 0.2 | 0.1 | 0.05 | 0 | 0 |
Cyanidin 3-O-(6''-malonyl-glucoside)
|
|
| 2 | 1 L | Single Dose | 0 | 1.5 | 1.1 | 0.8 | 0.5 | 0.25 |
Cyanidin 3-O-glucoside
|
|