Showing pharmacokinetics for metabolites after consumption of Chokeberry, extract in humans Metabolism

Kay C.D., Mazza G.J., Holub B.J. (2005) Anthocyanins exist in the circulation primarily as metabolites in adult men. J Nutr 135:2582-8 PubMed (16251615)

Urine analysed without enzymatic deconjugation

Cumulative Excretion in Urine (µg)
Number Dose Multiple Dose Duration Time (hours) Metabolite
0 2 4 8 12 24
1 7.1 g Single Dose 0 75 160 290 300 310
Cyanidin 3-O-galactoside
2 7.1 g Single Dose 0 10 50 70 100 110
Cyanidin 3-O-arabinoside
3 7.1 g Single Dose 0 20 50 75 110 130
Peonidin 3-O-galactoside
Chart?cht=lxy&chs=600x300&chf=bg,s,fafafa&chxt=x,x,y&chxr=0,0.0,24.240000000000002,2|2,0.0,313.1,20&chds=0.0,24.240000000000002,0.0,313.1,0.0,24.240000000000002,0.0,313.1,0.0,24.240000000000002,0.0,313.1&chxl=1:|time+after+ingestion+(hours)&chtt=cumulative+excretion+in+urine+(µg)&chxp=1,50|3,50&chd=t:0.0,2.0,4.0,8.0,12.0,24.0|0.0,75.0,160.0,290.0,300.0,310.0|0.0,2.0,4.0,8.0,12.0,24.0|0.0,10.0,50.0,70.0,100.0,110.0|0.0,2.0,4.0,8.0,12.0,24.0|0.0,20.0,50.0,75.0,110.0,130