Showing pharmacokinetics for Ellagic acid metabolite after consumption of Black raspberry, freeze-dried in humans Metabolism

Stoner G.D., Sardo C., Apseloff G., Mullet D., Wargo W., Pound V., Singh A., Sanders J., Aziz R., Casto B., Sun X. (2005) Pharmacokinetics of anthocyanins and ellagic acid in healthy volunteers fed freeze-dried black raspberries daily for 7 days. J Clin Pharmacol 45:1153-1164 PubMed (16172180)

Plasma and Urine analysed without enzymatic deconjugation

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Plasma Concentration (ng/mL)
Number Dose Multiple Dose Duration Time (hours) Polyphenol Source
Name as described in publication
0 0.25 1 2 4 12
1 45 g/day 7 days 1.5 1.6 2.8 2.8 1 0.8
freeze-dried black raspberry
Ml)&chxp=1,50|3,50&chd=t:0.0,0.25,1.0,2.0,4.0,12.0|1.5,1.6,2.8,2.8,1.0,0
Cumulative Excretion in Urine (µg)
Number Dose Multiple Dose Duration Time (hours) Polyphenol Source
Name as described in publication
0 4 8 12
1 45 g/day 7 days 1 9 12.3 13.3
freeze-dried black raspberry
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