Showing pharmacokinetics for metabolites after consumption of Onion [Red], fried in humans

Mullen W., Edwards C.A., Crozier A. (2006) Absorption, excretion and metabolite profiling of methyl-, glucuronyl-, glucosyl- and sulpho-conjugates of quercetin in human plasma and urine after ingestion of onions. Br J Nutr 96:107-16 PubMed (16869998)

Plasma analysed without enzymatic deconjugation

Plasma Concentration (nmol/L)
Number	Dose	Multiple Dose Duration	Time (hours)						Metabolite
			0	0.5	1	2	3	6
1	270 g	Single Dose	0	620	610	460	425	80	Quercetin 3'-sulfate
2	270 g	Single Dose	0	300	225	120	110	80	Quercetin 3-O-glucuronide
3	270 g	Single Dose	0	95	95	84	73	55	Isorhamnetin 3-O-glucuronide

L)&chxp=1,50|3,50&chd=t:0.0,0.5,1.0,2.0,3.0,6.0|0.0,620.0,610.0,460.0,425.0,80.0|0.0,0.5,1.0,2.0,3.0,6.0|0.0,300.0,225.0,120.0,110.0,80.0|0.0,0.5,1.0,2.0,3.0,6.0|0.0,95.0,95.0,84.0,73.0,55

Showing pharmacokinetics for metabolites after consumption of Onion [Red], fried in humans Metabolism

Plasma analysed without enzymatic deconjugation