Showing pharmacokinetics for metabolites after consumption of Tea [Green], infusion in humans Metabolism

Roowi S., Stalmach A., Mullen W., Lean M.E., Edwards C.A., Crozier A. (2010) Green tea flavan-3-ols: colonic degradation and urinary excretion of catabolites by humans. J Agric Food Chem 58:1296-304

Urine analysed without enzymatic deconjugation

Cumulative Excretion in Urine (µmol)
Number Dose Multiple Dose Duration Time (hours) Metabolite
0 2 5 8 24
1 300 mL Single Dose 0 0.6 0.7 0.8 2.2
Catechol
2 300 mL Single Dose 0 0.6 3.5 12 69
Pyrogallol
3 300 mL Single Dose 0 0 0.6 20.6 21
5-(3',4',5'-trihydroxyphenyl)-γ-valerolactone
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