Showing pharmacokinetics for Naringenin 4'-O-glucuronide metabolite after consumption of Orange [Blond], pure juice, fortified with hesperidin in humans Metabolism

Mullen W., Archeveque M.A., Edwards C.A., Matsumoto H., Crozier A. (2008) Bioavailability and metabolism of orange juice flavanones in humans: impact of a full-fat yogurt. J Agric Food Chem 56:11157-64 PubMed (19007165)

Urine analysed without enzymatic deconjugation

Show related sources from the same publication

Cumulative Excretion in Urine (nmol)
Number Dose Multiple Dose Duration Time (hours) Polyphenol Source
Name as described in publication
0 2 5 10 24
1 250 mL Single Dose 0 59 347 624 976
orange juice fortified with hesperidin
2 250 mL Single Dose 0 9.3 381.3 1032.3 1373
orange juice fortified with hesperidin
3 250 mL Single Dose 0 21 236 736 1034
orange juice fortified with hesperidin with 150 mL natural yoghurt
4 250 mL Single Dose 0 0 184 748 1301
orange juice fortified with hesperidin with 150 mL natural yoghurt
Chart?cht=lxy&chs=600x300&chf=bg,s,fafafa&chxt=x,x,y&chxr=0,0.0,24.240000000000002,2|2,0.0,1386.73,100&chds=0.0,24.240000000000002,0.0,1386.73,0.0,24.240000000000002,0.0,1386.73,0.0,24.240000000000002,0.0,1386.73,0.0,24.240000000000002,0.0,1386.73&chxl=1:|time+after+ingestion+(hours)&chtt=cumulative+excretion+in+urine+(nmol)&chxp=1,50|3,50&chd=t:0.0,2.0,5.0,10.0,24.0|0.0,59.0,347.0,624.0,976.0|0.0,2.0,5.0,10.0,24.0|0.0,9.3,381.3,1032.3,1373.0|0.0,2.0,5.0,10.0,24.0|0.0,21.0,236.0,736.0,1034.0|0.0,2.0,5.0,10.0,24.0|0.0,0.0,184.0,748.0,1301