Showing pharmacokinetics for Naringenin 4'-O-glucuronide metabolite after consumption of various sources Metabolism

Mullen W., Archeveque M.A., Edwards C.A., Matsumoto H., Crozier A. (2008) Bioavailability and metabolism of orange juice flavanones in humans: impact of a full-fat yogurt. J Agric Food Chem 56:11157-64 PubMed (19007165)

Urine analysed without enzymatic deconjugation

Cumulative Excretion in Urine (nmol)
Number Dose Multiple Dose Duration Time (hours) Polyphenol Source
Name as described in publication
0 2 5 10 24
1 250 mL Single Dose 0 59 347 624 976
orange juice fortified with hesperidin
2 250 mL Single Dose 0 21 236 736 1034
orange juice fortified with hesperidin with 150 mL natural yoghurt
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