Borges G., Mullen W., Mullan A., Lean M.E., Roberts S.A., Crozier A. (2010) Bioavailability of multiple components following acute ingestion of a polyphenol-rich juice drink. Mol Nutr Food Res 54 Suppl 2:S268-77 PubMed (20521274)

Urine analysed without enzymatic deconjugation

Cumulative Excretion in Urine (µmol)
Number Dose Multiple Dose Duration Time (hours) Metabolite
0 2 5 8 24
1 350 mL Single Dose 0 2 3.6 4.5 5
Epicatechin 3'-O-glucuronide
2 350 mL Single Dose 0 1.6 2.6 3.1 3.3
Phloretin 2'-O-glucuronide
3 350 mL Single Dose 0 0.03 0.2 0.4 0.4
Hesperetin 7-O-glucuronide
4 350 mL Single Dose 0 0.3 0.4 0.7 1.5
Caffeic acid 3-sulfate
5 350 mL Single Dose 0 0.3 0.6 2.4 5.9
Dihydrocaffeic acid 3-sulfate
6 350 mL Single Dose 0 0.3 0.5 1.4 3.6
Ferulic acid 4-sulfate
7 350 mL Single Dose 0 0.2 0.5 1 2
Dihydroferulic acid
8 350 mL Single Dose 0 0.08 0.18 0.38 0.68
Dihydroferulic acid 4-sulfate
9 350 mL Single Dose 0 0.6 1.1 2.2 6.3
Feruloylglycine
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