Showing pharmacokinetics for Urolithin B 3-O-glucuronide metabolite after consumption of Pomegranate, pure juice in humans Metabolism
Cerda B., Espin J.C., Parra S., Martinez P., Tomas-Barberan F.A. (2004) The potent in vitro antioxidant ellagitannins from pomegranate juice are metabolised into bioavailable but poor antioxidant hydroxy-6H-dibenzopyran-6-one derivatives by the colonic microflora of healt. Eur J Nutr 43:205-220
Plasma and Urine analysed without enzymatic deconjugation
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| Plasma Concentration (µmol/L) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (days) |
Polyphenol Source Name as described in publication |
|||||
| 0 | 1 | 2 | 3 | 4 | 5 | ||||
| 1 | 1 L/day | 5 days | 0 | 0 | 1.21 | 0.18 | 2.3 | 1.73 |
pomegranate juice
|