Cerda B., Espin J.C., Parra S., Martinez P., Tomas-Barberan F.A. (2004) The potent in vitro antioxidant ellagitannins from pomegranate juice are metabolised into bioavailable but poor antioxidant hydroxy-6H-dibenzopyran-6-one derivatives by the colonic microflora of healt. Eur J Nutr 43:205-220

Plasma analysed without enzymatic deconjugation

Plasma Concentration (µmol/L)
Number Dose Multiple Dose Duration Time (days) Metabolite
0 1 2 3 4 5
1 1 L/day 5 days 0 0 0.43 0.53 0.3 0.28
Urolithin C
2 1 L/day 5 days 0 0 1.21 0.18 2.3 1.73
Urolithin B 3-O-glucuronide
L)&chxp=1,50|3,50&chd=t:0.0,1.0,2.0,3.0,4.0,5.0|0.0,0.0,0.43,0.53,0.3,0.28|0.0,1.0,2.0,3.0,4.0,5.0|0.0,0.0,1.21,0.18,2.3,1