Showing pharmacokinetics for metabolites after consumption of Pomegranate, pure juice in humans Metabolism
Cerda B., Espin J.C., Parra S., Martinez P., Tomas-Barberan F.A. (2004) The potent in vitro antioxidant ellagitannins from pomegranate juice are metabolised into bioavailable but poor antioxidant hydroxy-6H-dibenzopyran-6-one derivatives by the colonic microflora of healt. Eur J Nutr 43:205-220
Plasma analysed without enzymatic deconjugation
| Plasma Concentration (µmol/L) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (days) | Metabolite | ||||||
| 0 | 1 | 2 | 3 | 4 | 5 | |||||
| 1 | 1 L/day | 5 days | 0 | 0 | 0.43 | 0.53 | 0.3 | 0.28 |
Urolithin C
|
|
| 2 | 1 L/day | 5 days | 0 | 0 | 1.21 | 0.18 | 2.3 | 1.73 |
Urolithin B 3-O-glucuronide
|
|