Showing pharmacokinetics for metabolites after consumption of Epicatechin gallate in rats Metabolism

Kohri T., Suzuki M., Nanjo F. (2003) Identification of metabolites of (-)-epicatechin gallate and their metabolic fate in the rat. J Agric Food Chem 51:5561-6 PubMed (12926915)

Urine analysed without enzymatic deconjugation

Cumulative Excretion in Urine (nmol)
Number Dose Multiple Dose Duration Time (hours) Metabolite
0 6 24 48 72
1 100 mg/kg bw Single Dose 0 0 372 1070 1070
3-Hydroxyphenylpropionic acid
2 100 mg/kg bw Single Dose 0 0 48 801 901
m-Coumaric acid
Chart?cht=lxy&chs=600x300&chf=bg,s,fafafa&chxt=x,x,y&chxr=0,0.0,72.72,5|2,0.0,1080.7,100&chds=0.0,72.72,0.0,1080.7,0.0,72.72,0.0,1080.7&chxl=1:|time+after+ingestion+(hours)&chtt=cumulative+excretion+in+urine+(nmol)&chxp=1,50|3,50&chd=t:0.0,6.0,24.0,48.0,72.0|0.0,0.0,372.0,1070.0,1070.0|0.0,6.0,24.0,48.0,72.0|0.0,0.0,48.0,801.0,901