Showing pharmacokinetics for metabolites after consumption of Lowbush blueberry, raw in rats Metabolism
Del Bo C., Ciappellano S., Klimis-Zacas D., Martini D., Gardana C., Riso P., Porrini M. (2010) Anthocyanin absorption, metabolism, and distribution from a wild blueberry-enriched diet (Vaccinium angustifolium) is affected by diet duration in the Sprague-Dawley rat. J Agric Food Chem 58:2491-7 PubMed (20030330)
Urine analysed without enzymatic deconjugation
| Cumulative Excretion in Urine (µg/24h) | |||||||
|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (weeks) | Metabolite | |||
| 0 | 4 | 8 | |||||
| 1 | 8 % of diet | 8 weeks | 0 | 42.7 | 84.5 |
Delphinidin 3-O-galactoside
|
|
| 2 | 8 % of diet | 8 weeks | 0 | 45.4 | 81.4 |
Delphinidin 3-O-glucoside
|
|
| 3 | 8 % of diet | 8 weeks | 0 | 60.9 | 123.9 |
Delphinidin 3-O-arabinoside
|
|
| 4 | 8 % of diet | 8 weeks | 0 | 45.5 | 108.5 |
Cyanidin 3-O-glucoside
|
|
| 5 | 8 % of diet | 8 weeks | 0 | 74.3 | 219.2 |
Cyanidin 3-O-galactoside
|
|
| 6 | 8 % of diet | 8 weeks | 0 | 29.2 | 46.9 |
Cyanidin 3-O-arabinoside
|
|
| 7 | 8 % of diet | 8 weeks | 0 | 61.3 | 153.5 |
Petunidin 3-O-galactoside
|
|
| 8 | 8 % of diet | 8 weeks | 0 | 38.4 | 60.1 |
Petunidin 3-O-glucoside
|
|
| 9 | 8 % of diet | 8 weeks | 0 | 157.6 | 323.9 |
Petunidin 3-O-arabinoside
|
|
| 10 | 8 % of diet | 8 weeks | 0 | 50.1 | 72.3 |
Petunidin 3-O-(6''-acetyl-glucoside)
|
|
| 11 | 8 % of diet | 8 weeks | 0 | 192.1 | 553.7 |
Peonidin 3-O-galactoside
|
|
| 12 | 8 % of diet | 8 weeks | 0 | 16.4 | 25.3 |
Peonidin 3-O-glucoside
|
|
| 13 | 8 % of diet | 8 weeks | 0 | 7.7 | 15.5 |
Peonidin 3-O-arabinoside
|
|
| 14 | 8 % of diet | 8 weeks | 0 | 55.4 | 98 |
Malvidin 3-O-galactoside
|
|
| 15 | 8 % of diet | 8 weeks | 0 | 4.3 | 13.3 |
Malvidin 3-O-glucoside
|
|
| 16 | 8 % of diet | 8 weeks | 0 | 5.6 | 9.8 |
Malvidin 3-O-arabinoside
|
|