Showing pharmacokinetics for 4-Hydroxybenzoic acid metabolite after consumption of Lowbush blueberry, raw in rats Metabolism

Del Bo C., Ciappellano S., Klimis-Zacas D., Martini D., Gardana C., Riso P., Porrini M. (2010) Anthocyanin absorption, metabolism, and distribution from a wild blueberry-enriched diet (Vaccinium angustifolium) is affected by diet duration in the Sprague-Dawley rat. J Agric Food Chem 58:2491-7 PubMed (20030330)

Plasma and Urine analysed without enzymatic deconjugation

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Plasma Concentration (ng/mL)
Number Dose Multiple Dose Duration Time (weeks) Polyphenol Source
Name as described in publication
0 4 8
1 8 % of diet 8 weeks 0 5 3.3
wild lowbush blueberry diet
Ml)&chxp=1,50|3,50&chd=t:0.0,4.0,8.0|0.0,5.0,3
Cumulative Excretion in Urine (µg/24h)
Number Dose Multiple Dose Duration Time (weeks) Polyphenol Source
Name as described in publication
0 4 8
1 8 % of diet 8 weeks 0 2749.4 3760.9
wild lowbush blueberry diet
24h)&chxp=1,50|3,50&chd=t:0.0,4.0,8.0|0.0,2749.4,3760