Holt R.R., Lazarus S.A., Sullards M.C., Zhu Q.Y., Schramm D.D., Hammerstone J.F., Fraga C.G., Schmitz H.H., Keen C.L. (2002) Procyanidin dimer B2 [epicatechin-(4beta-8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoa. Am J Clin Nutr 76:798-804 PubMed (12324293)

Plasma analysed after enzymatic deconjugation

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Plasma Concentration (nmol/L)
Number Dose Multiple Dose Duration Time (hours) Polyphenol Source
Name as described in publication
0 0.5 2 6
1 0.37 g/kg bw Single Dose 0 0.13 0.16 0.02
cocoa in 300 mL water