Showing pharmacokinetics for Procyanidin dimer B2 metabolite after consumption of Cocoa, powder in humans Metabolism
Holt R.R., Lazarus S.A., Sullards M.C., Zhu Q.Y., Schramm D.D., Hammerstone J.F., Fraga C.G., Schmitz H.H., Keen C.L. (2002) Procyanidin dimer B2 [epicatechin-(4beta-8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoa. Am J Clin Nutr 76:798-804 PubMed (12324293)
Plasma analysed after enzymatic deconjugation
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Plasma Concentration (nmol/L) | |||||||
---|---|---|---|---|---|---|---|
Number | Dose | Multiple Dose Duration | Time (hours) |
Polyphenol Source Name as described in publication |
|||
0 | 0.5 | 2 | 6 | ||||
1 | 0.37 g/kg bw | Single Dose | 0 | 16 | 41 | 15 |
cocoa in 300 mL water
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