Showing pharmacokinetics for metabolites after consumption of Epicatechin gallate in rats Metabolism
Kohri T., Suzuki M., Nanjo F. (2003) Identification of metabolites of (-)-epicatechin gallate and their metabolic fate in the rat. J Agric Food Chem 51:5561-6 PubMed (12926915)
Plasma analysed after enzymatic deconjugation
Plasma Concentration (pmol/mL) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Number | Dose | Multiple Dose Duration | Time (hours) | Metabolite | ||||||
0 | 0.5 | 1 | 6 | 24 | 48 | |||||
1 | 100 mg/kg bw | Single Dose | 0 | 0 | 0 | 214 | 562 | 0 |
5-(3',4',-dihydroxyphenyl)-γ-valerolactone
|
|
2 | 100 mg/kg bw | Single Dose | 0 | 233 | 73 | 2 | 0 | 0 |
(-)-Epicatechin 3-O-gallate
|