Showing pharmacokinetics for Isorhamnetin metabolite after consumption of Isorhamnetin in rats Metabolism
Lan K., Jiang X., He J. (2007) Quantitative determination of isorhamnetin, quercetin and kaempferol in rat plasma by liquid chromatography with electrospray ionization tandem mass spectrometry and its application to the pharmacokin. Rapid Commun Mass Spectrom 21:112-20
Plasma analysed after enzymatic deconjugation
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Plasma Concentration (ng/mL) | |||||||||
---|---|---|---|---|---|---|---|---|---|
Number | Dose | Multiple Dose Duration | Time (hours) |
Polyphenol Source Name as described in publication |
|||||
0 | 1.5 | 4 | 10 | 24 | 60 | ||||
1 | 0.25 mg/kg bw | Single Dose | 0 | 11 | 32 | 44 | 23 | 2 |
isorhamnetin
|
2 | 0.5 mg/kg bw | Single Dose | 0 | 20 | 49 | 39 | 24 | 3 |
isorhamnetin
|
3 | 1 mg/kg bw | Single Dose | 0 | 26 | 31 | 54 | 31 | 9 |
isorhamnetin
|