Showing pharmacokinetics for Naringenin metabolite after consumption of Naringenin in rats Metabolism

Ma Y., Li P., Chen D., Fang T., Li H., Su W. (2006) LC/MS/MS quantitation assay for pharmacokinetics of naringenin and double peaks phenomenon in rats plasma. Int J Pharm 307:292-9 PubMed (16289985)

Plasma analysed after enzymatic deconjugation

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Plasma Concentration (ng/mL)
Number Dose Multiple Dose Duration Time (hours) Polyphenol Source
Name as described in publication
0 2 4 6 12 24
1 30 mg/kg bw Single Dose 0 8000 4000 0 0 0
naringenin
2 90 mg/kg bw Single Dose 0 28000 10000 8000 0 0
naringenin
3 270 mg/kg bw Single Dose 0 45000 41000 30000 16000 0
naringenin
Ml)&chxp=1,50|3,50&chd=t:0.0,2.0,4.0,6.0,12.0,24.0|0.0,8000.0,4000.0,0.0,0.0,0.0|0.0,2.0,4.0,6.0,12.0,24.0|0.0,28000.0,10000.0,8000.0,0.0,0.0|0.0,2.0,4.0,6.0,12.0,24.0|0.0,45000.0,41000.0,30000.0,16000.0,0