Showing pharmacokinetics for metabolites after consumption of Procyanidin dimer B2 in rats Metabolism
Baba S., Osakabe N., Natsume M., Terao J. (2002) Absorption and urinary excretion of procyanidin B2 [epicatechin-(4beta-8)-epicatechin] in rats. Free Radic Biol Med 33:142-8
Plasma analysed after enzymatic deconjugation
| Plasma Concentration (µmol/L) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (minutes) | Metabolite | ||||||
| 0 | 30 | 60 | 120 | 180 | 300 | |||||
| 1 | 50 mg/kg bw | Single Dose | 0 | 0.21 | 0.2 | 0.19 | 0.1 | 0.1 |
(-)-Epicatechin
|
|
| 2 | 50 mg/kg bw | Single Dose | 0 | 0.13 | 0.12 | 0.1 | 0.05 | 0.04 |
3'-O-Methylepicatechin
|
|
| 3 | 50 mg/kg bw | Single Dose | 0 | 0.5 | 0.42 | 0.21 | 0.15 | 0.05 |
Procyanidin dimer B2
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