Showing pharmacokinetics for metabolites after consumption of Grapefruit, extract, in capsule in dogs

Mata-Bilbao Mde L., Andres-Lacueva C., Roura E., Jauregui O., Escribano E., Torre C., Lamuela-Raventos R.M. (2007) Absorption and pharmacokinetics of grapefruit flavanones in beagles. Br J Nutr 98:86-92 PubMed (17391560)

Plasma analysed without enzymatic deconjugation

Plasma Concentration (nmol/L)
Number	Dose	Multiple Dose Duration	Time (minutes)						Metabolite
			0	10	20	40	240	480
1	400 g	Single Dose	0	70	48	90	40	5	Naringin
2	400 g	Single Dose	0	25	25	10	0	0	Naringenin

L)&chxp=1,50|3,50&chd=t:0.0,10.0,20.0,40.0,240.0,480.0|0.0,70.0,48.0,90.0,40.0,5.0|0.0,10.0,20.0,40.0,240.0,480.0|0.0,25.0,25.0,10.0,0.0,0

Showing pharmacokinetics for metabolites after consumption of Grapefruit, extract, in capsule in dogs Metabolism

Plasma analysed without enzymatic deconjugation