Showing pharmacokinetics for metabolites after consumption of Coffee bean [green], extract, drink in humans Metabolism
Matsui Y., Nakamura S., Kondou N., Takasu Y., Ochiai R., Masukawa Y. (2007) Liquid chromatography-electrospray ionization-tandem mass spectrometry for simultaneous analysis of chlorogenic acids and their metabolites in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci 858:96-105 PubMed (17766198)
Plasma analysed without enzymatic deconjugation
| Plasma Concentration (ng/mL) | |||||||
|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (hours) | Metabolite | |||
| 0 | 1 | 3 | |||||
| 1 | 250 mL | Single Dose | 0 | 6.64 | 303 |
3-Feruloylquinic acid
|
|
| 2 | 250 mL | Single Dose | 0 | 13.87 | 7.01 |
5-Feruloylquinic acid
|
|
| 3 | 250 mL | Single Dose | 0 | 3.8 | 2.78 |
4-Feruloylquinic acid
|
|
| 4 | 250 mL | Single Dose | 0 | 0.89 | 0 |
Ferulic acid
|
|
| 5 | 250 mL | Single Dose | 0 | 3.91 | 2.5 |
3-Caffeoylquinic acid
|
|
| 6 | 250 mL | Single Dose | 0 | 7.39 | 4.05 |
5-Caffeoylquinic acid
|
|
| 7 | 250 mL | Single Dose | 0 | 6.81 | 4.08 |
5-Caffeoylquinic acid
|
|