Showing pharmacokinetics for metabolites after consumption of Cranberry juice, cocktail (27% cranberry juice) in humans Metabolism

Zhang K., Zuo Y. (2004) GC-MS determination of flavonoids and phenolic and benzoic acids in human plasma after consumption of cranberry juice. Journal of Agricultural and Food Chemistry 52:222-227 PubMed (14733499)

Plasma analysed without enzymatic deconjugation

Plasma Concentration (µg/mL)
Number Dose Multiple Dose Duration Time (minutes) Metabolite
0 45 270
1 1800 mL Single Dose 0 4.4 3.11
Benzoic acid
2 1800 mL Single Dose 0 0.98 0.42
2-Hydroxybenzoic acid
3 1800 mL Single Dose 0 1.4 1.12
4-Hydroxyphenylacetic acid
4 1800 mL Single Dose 0 2.06 0.16
2,3-Dihydroxybenzoic acid
5 1800 mL Single Dose 0 0.61 0.84
2,4-Dihydroxybenzoic acid
6 1800 mL Single Dose 0 0 0.31
Ferulic acid
7 1800 mL Single Dose 0 0 1.5
Sinapic acid
Ml)&chxp=1,50|3,50&chd=t:0.0,45.0,270.0|0.0,4.4,3.11|0.0,45.0,270.0|0.0,0.98,0.42|0.0,45.0,270.0|0.0,1.4,1.12|0.0,45.0,270.0|0.0,2.06,0.16|0.0,45.0,270.0|0.0,0.61,0.84|0.0,45.0,270.0|0.0,0.0,0.31|0.0,45.0,270.0|0.0,0.0,1