Showing pharmacokinetics for metabolites after consumption of Perilla frutescens tablet in humans Metabolism
Baba S., Osakabe N., Natsume M., Yasuda A., Muto Y., Hiyoshi K., Takano H., Yoshikawa T., Terao J. (2005) Absorption, metabolism, degradation and urinary excretion of rosmarinic acid after intake of Perilla frutescens extract in humans. Eur J Nutr 44:1-9 PubMed (15309457)
Plasma analysed without enzymatic deconjugation
| Plasma Concentration (nmol/L) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (hours) | Metabolite | ||||||
| 0 | 0.5 | 1 | 2 | 6 | 24 | |||||
| 1 | 1 tablet | Single Dose | 0 | 21 | 21 | 6 | 0 | 0 |
Rosmarinic acid
|
|
| 2 | 1 tablet | Single Dose | 0 | 4 | 39 | 15 | 0 | 0 |
3-O-Methylrosmarinic acid
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|