Showing pharmacokinetics for metabolites after consumption of Olive, oil, virgin in humans Metabolism
Suarez M., Romero M.P., Macia A., Valls R.M., Fernandez S., Sola R., Motilva M.J. (2009) Improved method for identifying and quantifying olive oil phenolic compounds and their metabolites in human plasma by microelution solid-phase extraction plate and liquid chromatography-tandem mass sp. J Chromatogr B Analyt Technol Biomed Life Sci 877:4097-106
Plasma analysed without enzymatic deconjugation
| Plasma Concentration (µmol/L) | |||||||
|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (minutes) | Metabolite | |||
| 0 | 60 | 120 | |||||
| 1 | 30 mL | Single Dose | 0 | 0 | 7.55 |
Tyrosol 4-sulfate
|
|
| 2 | 30 mL | Single Dose | 0 | 0 | 0.03 |
Hydroxytyrosol
|
|
| 3 | 30 mL | Single Dose | 0 | 1.24 | 0.11 |
Homovanillic acid 4-sulfate
|
|
| 4 | 30 mL | Single Dose | 0 | 25.14 | 4.66 |
Vanillin 4-sulfate
|
|
| 5 | 30 mL | Single Dose | 0 | 0.05 | 0.04 |
Vanillic acid 4-sulfate
|
|
| 6 | 30 mL | Single Dose | 0 | 0 | 0.31 |
3,4-DHPEA-EDA
|
|
| 7 | 30 mL | Single Dose | 0 | 0 | 0.01 |
p-HPEA-EDA
|
|
| 8 | 30 mL | Single Dose | 0 | 0.74 | 1.02 |
Vanillin
|
|
| 9 | 30 mL | Single Dose | 0 | 3.26 | 0 |
Vanillic acid
|
|
| 10 | 30 mL | Single Dose | 0 | 6.32 | 3.53 |
4-Hydroxybenzoic acid
|
|