Showing pharmacokinetics for metabolites after consumption of Dalbergia odorifera, extract in rats Metabolism
Liu R., Sun J., Bi K., Guo D.A. (2005) Identification and determination of major flavonoids in rat serum by HPLC-UV and HPLC-MS methods following oral administration of Dalbergiaodorifera extract. J Chromatogr B Analyt Technol Biomed Life Sci 829:35-44 PubMed (16233995)
Plasma analysed without enzymatic deconjugation
Plasma Concentration (µg/mL) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Number | Dose | Multiple Dose Duration | Time (minutes) | Metabolite | ||||||
0 | 30 | 60 | 80 | 240 | 1440 | |||||
1 | 1.5 g/kg bw | Single Dose | 0 | 6 | 2.5 | 2.5 | 0 | 0 |
Formononetin
|
|
2 | 1.5 g/kg bw | Single Dose | 0 | 26 | 14 | 14 | 7.5 | 2.5 |
4'-Methoxy-2',3,7-trihydroxyisoflavanone
|
|
3 | 1.5 g/kg bw | Single Dose | 0 | 9 | 4 | 3.5 | 1 | 0 |
Vestitone
|
|
4 | 1.5 g/kg bw | Single Dose | 0 | 12.5 | 7.5 | 6 | 4 | 0 |
Sativanone
|