Showing pharmacokinetics for metabolites after consumption of Gallic acid ethyl ester in rats Metabolism
Gao S., Zhan Q., Li J., Yang Q., Li X., Chen W., Sun L. (2010) LC-MS/MS method for the simultaneous determination of ethyl gallate and its major metabolite in rat plasma. Biomed Chromatogr 24:472-8 PubMed (19688816)
Plasma analysed without enzymatic deconjugation
Plasma Concentration (ng/mL) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Number | Dose | Multiple Dose Duration | Time (minutes) | Metabolite | ||||||
0 | 3 | 6 | 30 | 60 | 240 | |||||
1 | 20 mg/kg bw | Single Dose | 0 | 75 | 145 | 90 | 25 | 0 |
Gallic acid
|
|
2 | 20 mg/kg bw | Single Dose | 0 | 425 | 475 | 175 | 25 | 10 |
Gallic acid ethyl ester
|