Showing pharmacokinetics for Naringenin metabolite after consumption of Naringenin in rats Metabolism
Ma Y., Li P., Chen D., Fang T., Li H., Su W. (2006) LC/MS/MS quantitation assay for pharmacokinetics of naringenin and double peaks phenomenon in rats plasma. Int J Pharm 307:292-9 PubMed (16289985)
Plasma analysed without enzymatic deconjugation
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Plasma Concentration (ng/mL) | |||||||||
---|---|---|---|---|---|---|---|---|---|
Number | Dose | Multiple Dose Duration | Time (hours) |
Polyphenol Source Name as described in publication |
|||||
0 | 2 | 4 | 6 | 12 | 24 | ||||
1 | 30 mg/kg bw | Single Dose | 0 | 0 | 0 | 0 | 0 | 0 |
naringenin
|
2 | 90 mg/kg bw | Single Dose | 0 | 1000 | 900 | 1500 | 800 | 0 |
naringenin
|
3 | 270 mg/kg bw | Single Dose | 0 | 2600 | 1900 | 1500 | 800 | 0 |
naringenin
|