Showing pharmacokinetics for metabolites after consumption of Punicalagin in rats Metabolism
Cerda B., Llorach R., Ceron J.J., Espin J.C., Tomas-Barberan F.A. (2003) Evaluation of the bioavailability and metabolism in the rat of punicalagin, an antioxidant polyphenol from pomegranate juice. Eur J Nutr 42:18-28 PubMed (12594538)
Plasma analysed without enzymatic deconjugation
| Plasma Concentration (µg/mL) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (days) | Metabolite | ||||||
| 0 | 7 | 14 | 21 | 29 | 37 | |||||
| 1 | 6 % of diet | 37 days | 0 | 0.75 | 0.3 | 0.6 | 0.3 | 0.35 |
Ellagic acid
|
|
| 2 | 6 % of diet | 37 days | 0 | 29 | 28.5 | 28.5 | 28.5 | 29.5 |
Punicalagin
|
|
| 3 | 6 % of diet | 37 days | 0 | 0 | 0 | 1 | 3 | 6 |
Gallagic acid
|
|