Showing pharmacokinetics for metabolites after consumption of Rhizoma drynariae, extract in rats Metabolism
Xiao-Hong LI Z.-L.X., Shan LU, Yi Z, Fa-Mei LI (2010) Pharmacokinetics of Naringin and its Metabolite Naringenin in Rats after Oral Administration of Rhizoma Drynariae Extract Assayed by UPLC-MS/MS. Chinese Journal of Natural Medicines 8:40-46
Plasma analysed without enzymatic deconjugation
| Plasma Concentration (ng/mL) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Number | Dose | Multiple Dose Duration | Time (hours) | Metabolite | ||||||
| 0 | 0.5 | 1 | 4 | 8 | 24 | |||||
| 1 | 70 g/kg bw | Single Dose | 0 | 1900 | 1100 | 250 | 200 | 0 |
Naringin
|
|
| 2 | 70 g/kg bw | Single Dose | 0 | 40 | 50 | 100 | 175 | 0 |
Naringenin
|
|