Showing all polyphenol metabolites originating from consumption of Shuangdan granules Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| rat studies | ||||||||||||
| 2,4-Dihydroxyacetophenone 5-sulfate | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||
| 2-Hydroxy-4-methoxyacetophenone 5-sulfate | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||
| Caffeic acid | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||
| Danshensu | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||
| Gallic acid | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||
| Lithospermic acid | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||
| Paeoniflorin | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||
| Paeonol | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||
| Protocatechuic aldehyde | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||
| Resacetophenone | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||
| Rosmarinic acid | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||
| Salvianolic acid B | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||
| Salvianolic acid C | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||
| Salvianolic acid D | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||
| Salvianolic acid G | Not applicable | 12 g/100 g bw/day | 1 days | 6 | Detected (unquantified) | PAN 2006 | ||||||