Showing all polyphenol metabolites originating from consumption of (-)-Epicatechin and (+)-catechin, mixture Metabolism
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| rat studies | ||||||||||||
| (+)-Catechin | Not applicable | 172 µmol/kg bw | Single dose | 5 | 7.21 µmol after 24 hours | 56.5 |
|
BABA 2001_02 | ||||
| (-)-Epicatechin | Not applicable | 172 µmol/kg bw | Single dose | 5 | 9.43 µmol after 24 hours | 76.5 |
|
BABA 2001_02 | ||||
| 3'-O-Methylcatechin | Not applicable | 172 µmol/kg bw | Single dose | 5 | 2.53 µmol after 24 hours | 18.9 |
|
BABA 2001_02 | ||||
| 3'-O-Methylepicatechin | Not applicable | 172 µmol/kg bw | Single dose | 5 | 4.51 µmol after 24 hours | 76.5 |
|
BABA 2001_02 | ||||
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| rat studies | ||||||||||||
| (+)-Catechin | Not applicable | 172 µmol/kg bw | Single dose | 5 | 1.05 µmol after 24 hours | 0.15 |
|
BABA 2001_02 | ||||
| (-)-Epicatechin | Not applicable | 172 µmol/kg bw | Single dose | 5 | 5.54 µmol after 24 hours | 0.82 |
|
BABA 2001_02 | ||||
| 3'-O-Methylcatechin | Not applicable | 172 µmol/kg bw | Single dose | 5 | 0.73 µmol after 24 hours | 0 |
|
BABA 2001_02 | ||||
| 3'-O-Methylepicatechin | Not applicable | 172 µmol/kg bw | Single dose | 5 | 2.65 µmol after 24 hours | 0.82 |
|
BABA 2001_02 | ||||