Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
rat studies
(-)-Epicatechin Not applicable 50 mg/kg bw Single dose 5 0.5 0.25 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 BABA 2002
3'-O-Methylepicatechin Not applicable 50 mg/kg bw Single dose 5 0.5 0.15 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 BABA 2002
Procyanidin dimer B2 Not applicable 50 mg/kg bw Single dose 5 0.5 0.5 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 BABA 2002
  Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
rat studies
(-)-Epicatechin Not applicable 50 mg/kg bw Single dose 5 0.02 12.5 nmol after 18 hours BABA 2002
3'-O-Methylepicatechin Not applicable 50 mg/kg bw Single dose 5 0.02 12.8 nmol after 18 hours BABA 2002
Procyanidin dimer B2 Not applicable 50 mg/kg bw Single dose 5 0.34 83 nmol after 18 hours BABA 2002