Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
Hesperetin Food administered
Generic food
150 g Single dose 20 4.53 7 0.09 376 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 BRETT 2009
Naringenin Food administered
Generic food
150 g Single dose 20 12.5 5.88 0.08 230 Graph a9d716975d07e4a7e41abb50e7f45e82a5a61800f83ed43664b0781ff2caee59 BRETT 2009
  Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
Hesperetin 3'-O-glucuronide Food administered
Generic food
150 g Single dose 20 Detected (unquantified) Detected (unquantified) BRETT 2009
Hesperetin 7-O-glucuronide Food administered
Generic food
150 g Single dose 20 Detected (unquantified) Detected (unquantified) BRETT 2009
Naringenin 4'-O-glucuronide Food administered
Generic food
150 g Single dose 20 Detected (unquantified) Detected (unquantified) BRETT 2009
Naringenin 7-O-glucuronide Food administered
Generic food
150 g Single dose 20 Detected (unquantified) Detected (unquantified) BRETT 2009