Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
Hesperetin Generic food 400 mL Single dose 10 8.9 28.3 µmol after 48 hours 6.3 1.48 4145.1 VALLEJO 2010
400 mL Single dose 10 4.6 30.8 µmol after 48 hours 7.3 1.15 4434.4 VALLEJO 2010
400 mL Single dose 10 1.7 5.7 µmol after 48 hours 6.4 0.36 945.6 VALLEJO 2010
400 mL Single dose 10 5.4 9 µmol after 48 hours VALLEJO 2010
400 mL Single dose 10 4.7 4.7 µmol after 48 hours 6 0.15 503.6 VALLEJO 2010
Naringenin Generic food 400 mL Single dose 10 5.4 18.9 µmol after 48 hours 6.4 0.44 961.1 VALLEJO 2010
400 mL Single dose 10 1 18.7 µmol after 48 hours 5.9 0.53 1464.8 VALLEJO 2010
400 mL Single dose 10 0.7 2.6 µmol after 48 hours 5.7 0.44 735.2 VALLEJO 2010
400 mL Single dose 10 2.6 4.8 µmol after 48 hours VALLEJO 2010
400 mL Single dose 10 0.5 2.3 µmol after 48 hours 5 0.06 200.6 VALLEJO 2010