Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
Homovanillyl alcohol Food administered
50 mL Single dose 6 1567 µg after 24 hours VISIOLI 2000_02
Hydroxytyrosol Food administered
50 mL Single dose 6 1024 µg after 24 hours VISIOLI 2000_02
50 mL Single dose 6 40 1600 µg after 24 hours VISIOLI 2000_01
Tyrosol Not applicable 50 mL Single dose 6 24 1600 µg after 24 hours VISIOLI 2000_01
  Urine Plasma  
Polyphenol metabolite Composition of the [polyphenol] source Doses
administered
Dose
duration
Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
Hydroxytyrosol Not applicable 50 mL Single dose 6 15 µg after 24 hours VISIOLI 2000_01
Tyrosol Not applicable 50 mL Single dose 6 30 µg after 24 hours VISIOLI 2000_01