Showing experiments where (-)-Epigallocatechin 3-O-gallate has been detected in biofluids Metabolism

  Urine Plasma  
[polyphenol] source used in experiment Source composition Doses administered Dose duration Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
epigallocatechin gallate Not applicable 2 mg/kg bw Single dose 4 2 0.09 2.5 236.6 MENG 2002
epigallocatechin gallate Not applicable 200 mg Single dose 12 Graph LOKE 2009
green tea solids in water Food administered
 20 mg/kg bw Single dose 4 26.7 Graph 2 0.14 2.7 668 Graph MENG 2002
mouse studies
epigallocatechin gallate Not applicable 0.3 % of ad libitum drinking fluid 0 5 Detected (unquantified) 90.6 after 3 days MENG 2002
green tea solids in water Food administered
 0.6 % of ad libitum drinking fluid 0 5 Detected (unquantified) 63.3 after 3 days MENG 2002
  Urine Plasma  
[polyphenol] source used in experiment Source composition Doses administered Dose duration Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
Choladi green tea Food administered
Generic food 		500 mL Single dose 10 1.9 0.05 1 0.17 Graph STALMACH 2009_01
ready-to-drink green tea Food administered
Generic food 		400 mL Single dose 5 1.4 0.07 Graph DEL RIO 2010
dog studies
green tea extract in capsules Food administered
 200 mg Single dose 2 312.3 nmol/L after 1.5 hours MATA-BILBAO 2007_01
green tea extract in capsules Food administered
 200 mg Single dose 12 1.1 0.3 71 Graph MATA-BILBAO 2008