Urine Plasma  
[polyphenol] source used in experiment Source composition Doses administered Dose duration Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
naringin powder Not applicable 500 mg Single dose 6 0.02 Graph ISHII 2000
rat studies
B. falcatum and F. aurantii herbs Not applicable 1.35 g/kg bw 7 days 5 16.3 ng/mL after 12 hours LI 2004
naringin dissolved in 50% PEG400 Not applicable 746.7 mg/kg bw Single dose 6 0.75 6.51 5.34 6026.32 Graph FANG 2006
Rhizoma drynariae Not applicable 70 g/kg bw Single dose 6 0.67 0 4.1 3.23 Graph XIAO-HONG LI 2010
dog studies
capsules containing grapefruit extract Food administered
400 g Single dose 8 1.33 0 23.16 Graph MATA-BILBAO 2007_02